Journal article
Adhiraj Roy, Q. J. Wang
Molecular and Cellular Pharmacology, 2017
Molecular and Cellular Pharmacology, 2017
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APA
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Roy, A., & Wang, Q. J. (2017). Protein Kinase D: A Potential Therapeutic Target in Prostate Cancer. Molecular and Cellular Pharmacology.
Chicago/Turabian
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Roy, Adhiraj, and Q. J. Wang. “Protein Kinase D: A Potential Therapeutic Target in Prostate Cancer.” Molecular and Cellular Pharmacology (2017).
MLA
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Roy, Adhiraj, and Q. J. Wang. “Protein Kinase D: A Potential Therapeutic Target in Prostate Cancer.” Molecular and Cellular Pharmacology, 2017.
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@article{adhiraj2017a,
title = {Protein Kinase D: A Potential Therapeutic Target in Prostate Cancer},
year = {2017},
journal = {Molecular and Cellular Pharmacology},
author = {Roy, Adhiraj and Wang, Q. J.}
}
Abstract
Protein kinase D (PKD) belongs to a family of serine/threonine kinases in the calcium/calmodulin-dependent kinase superfamily. It modulates a number of signal transduction pathways involved in regulation of cell proliferation, survival, migration, angiogenesis, regulation of gene expression, and protein/membrane trafficking, mediated by variety of stimuli such as growth factors, hormones, and cellular stresses. Although its role in cancer progression remains elusive, current literature supports a potential tumor promoting function of the selective PKD isoforms in prostate cancer, making them promising therapeutic targets for cancer treatment.