Journal article
Adhiraj Roy, S. Hashmi, Zerui Li, Angela D. Dement, Kyu Hong Cho, Jeong‐Ho Kim
Molecular Biology of the Cell, 2016
Molecular Biology of the Cell, 2016
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APA
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Roy, A., Hashmi, S., Li, Z., Dement, A. D., Cho, K. H., & Kim, J. H. (2016). The glucose metabolite methylglyoxal inhibits expression of the glucose transporter genes by inactivating the cell surface glucose sensors Rgt2 and Snf3 in yeast. Molecular Biology of the Cell.
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Roy, Adhiraj, S. Hashmi, Zerui Li, Angela D. Dement, Kyu Hong Cho, and Jeong‐Ho Kim. “The Glucose Metabolite Methylglyoxal Inhibits Expression of the Glucose Transporter Genes by Inactivating the Cell Surface Glucose Sensors Rgt2 and Snf3 in Yeast.” Molecular Biology of the Cell (2016).
MLA
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Roy, Adhiraj, et al. “The Glucose Metabolite Methylglyoxal Inhibits Expression of the Glucose Transporter Genes by Inactivating the Cell Surface Glucose Sensors Rgt2 and Snf3 in Yeast.” Molecular Biology of the Cell, 2016.
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@article{adhiraj2016a,
title = {The glucose metabolite methylglyoxal inhibits expression of the glucose transporter genes by inactivating the cell surface glucose sensors Rgt2 and Snf3 in yeast},
year = {2016},
journal = {Molecular Biology of the Cell},
author = {Roy, Adhiraj and Hashmi, S. and Li, Zerui and Dement, Angela D. and Cho, Kyu Hong and Kim, Jeong‐Ho}
}
Abstract
Methylglyoxal (MG) is a cytotoxic by-product of glycolysis. MG inhibits the growth of glucose-fermenting yeast cells by inhibiting glycolysis. MG does so by inducing endocytosis and degradation of the cell-surface glucose sensors Rgt2 and Snf3, which are required for glucose induction of HXT (glucose transporter) gene expression.